Treatment Options

Curative / Long-term Management

• Targeted Therapy (Tyrosine Kinase Inhibitors, TKIs):

  • First-line treatment (e.g., Imatinib, Dasatinib, Nilotinib)

  • Blocks the BCR-ABL gene responsible for abnormal cell growth

• Chemotherapy: Occasionally used in accelerated or blast phase

• Stem Cell / Bone Marrow Transplant: Considered for resistant or advanced CML

• Interferon Therapy: Rarely used, in specific situations

Supportive Care

• Blood transfusions for anemia

• Antibiotics or antivirals to prevent infections

• Regular monitoring of blood counts and molecular response

CML Treatment Cost in India

Table 1: Average Chronic Myeloid Leukemia Treatment Cost in India

Factors Affecting Cost

1. Type and stage of CML – Chronic, accelerated, or blast phase

2. Treatment approach – TKI therapy vs. transplant

3. Hospital facilities – Specialized cancer centers charge more

4. Frequency of monitoring – Regular molecular tests and blood counts

5. Supportive care requirements – Transfusions, infection management, or complications

Who Should Get CML Treatment?

• Patients diagnosed with chronic, accelerated, or blast-phase CML

• Individuals with BCR-ABL positive mutation

• Patients with resistant disease requiring second-line therapy

• Individuals referred by hematologists or oncologists

Benefits of Timely Treatment

• Long-term disease control and prolonged survival

• Prevention of progression to accelerated or blast phase

• Improved quality of life with oral targeted therapy

• Reduced complications with regular monitoring